COPB1 and RHOQ

Number of citations of the paper that reports this interaction (PubMedID 12134073)
34

Data Source:
HPRD (in vivo)

		COPB1	RHOQ
Description		COPI coat complex subunit beta 1	ras homolog family member Q
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Transport Vesicle Secretory Granule Membrane Intracellular Membrane-bounded Organelle Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell Cortex Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	GTPase Activity Profilin Binding GTP Binding Protein Kinase Binding GBD Domain Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Viral Process Neutrophil Degranulation	Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Translocation of SLC2A4 (GLUT4) to the plasma membrane Rho GTPase cycle RHO GTPases regulate CFTR trafficking
Drugs
Diseases
GWAS		HDL cholesterol ( 26780889) HDL cholesterol levels ( 28334899) Height ( 31562340) High chromosomal aberration frequency (total) ( 31586183) Vitamin D levels ( 25208829)
Interacting Genes		38 interacting genes: ADAM19 APP ARCN1 ARF1 COPE COPG1 COPG2 ERBIN FOXB1 GORAB GRB2 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 LINC00839 LZTS2 NUB1 PDGFRB PRKCE RGS2 RGS4 RHOQ SCYL1 SERTAD1 SNTA1 SPTBN1 TANK TAPBP TMED10 TRIM37 UBC UBQLN4 VPS18 WBP2 XRCC6	18 interacting genes: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL
Entrez ID		1315	23433
HPRD ID		02981	05791
Ensembl ID		ENSG00000129083	ENSG00000119729
Uniprot IDs		P53618	D6W5A7 P17081 V9HWD0
PDB IDs			2ATX
Enriched GO Terms of Interacting Partners?
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