COL6A2 and COX6A2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		COL6A2	COX6A2
Description		collagen type VI alpha 2 chain	cytochrome c oxidase subunit 6A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Protein-containing Complex Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Mitochondrial Respiratory Chain Complex IV
	Molecular Function	Protein Binding Collagen Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	Cytochrome-c Oxidase Activity Enzyme Regulator Activity
	Biological Process	Growth Plate Cartilage Chondrocyte Morphogenesis Cell Adhesion Response To Glucose Extracellular Matrix Organization	Generation Of Precursor Metabolites And Energy Mitochondrial Electron Transport, Cytochrome C To Oxygen Aerobic Respiration Regulation Of Catalytic Activity Proton Transmembrane Transport
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization
Drugs			Cholic Acid N-Formylmethionine
Diseases		Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
GWAS		Central corneal thickness ( 29760442) Height ( 31562340) Intraocular pressure ( 29235454)
Interacting Genes		6 interacting genes: ABCD3 COL6A1 COX6A2 FN1 SIRPA SLC38A3	5 interacting genes: APP COL6A2 MRPL12 POT1 SNX21
Entrez ID		1292	1339
HPRD ID		02110	03598
Ensembl ID		ENSG00000142173	ENSG00000156885
Uniprot IDs		A0A384MDP3 P12110	Q02221
PDB IDs
Enriched GO Terms of Interacting Partners?
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