COL6A2 and SLC38A3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		COL6A2	SLC38A3
Description		collagen type VI alpha 2 chain	solute carrier family 38 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Protein-containing Complex Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding Collagen Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength	L-histidine Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-asparagine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity Symporter Activity Antiporter Activity
	Biological Process	Growth Plate Cartilage Chondrocyte Morphogenesis Cell Adhesion Response To Glucose Extracellular Matrix Organization	Amino Acid Transmembrane Transport Sodium Ion Transport Amino Acid Transport Asparagine Transport Glutamine Transport Brain Development Female Pregnancy L-alanine Transport Histidine Transport Cellular Response To Potassium Ion Starvation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Acidic PH L-histidine Transmembrane Transport Positive Regulation Of Glutamine Transport
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization	Amino acid transport across the plasma membrane
Drugs			Histidine L-Asparagine
Diseases		Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
GWAS		Central corneal thickness ( 29760442) Height ( 31562340) Intraocular pressure ( 29235454)	Body mass index ( 26426971) Conotruncal heart defects (maternal effects) ( 28468790) Sleep duration (short sleep) ( 30846698) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		6 interacting genes: ABCD3 COL6A1 COX6A2 FN1 SIRPA SLC38A3	3 interacting genes: COL6A2 HMGN1 SETDB1
Entrez ID		1292	10991
HPRD ID		02110	11980
Ensembl ID		ENSG00000142173	ENSG00000188338
Uniprot IDs		A0A384MDP3 P12110	Q99624
PDB IDs
Enriched GO Terms of Interacting Partners?
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