CCR8 and CCL4

Number of citations of the paper that reports this interaction (PubMedID 9521068)
19

Data Source:
HPRD (in vivo, in vitro)

		CCR8	CCL4
Description		C-C motif chemokine receptor 8	C-C motif chemokine ligand 4
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding	Cytokine Activity Protein Binding Chemokine Activity CCR1 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Identical Protein Binding CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Immune Response Cell Adhesion G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Monocyte Chemotaxis Inflammatory Response Immune Response Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Response To Toxic Substance Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Transcription Lymphocyte Chemotaxis Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transport Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Medication use (thyroid preparations) ( 31015401)	Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		6 interacting genes: CCL1 CCL16 CCL17 CCL4 TPST1 TPST2	8 interacting genes: ACKR2 CCL3 CCR1 CCR3 CCR5 CCR8 CXCL8 SLC30A2
Entrez ID		1237	6351
HPRD ID		03497	01657
Ensembl ID		ENSG00000179934	ENSG00000275302
Uniprot IDs		P51685	P13236
PDB IDs			1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?
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