CCL4 and SLC30A2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCL4	SLC30A2
Description		C-C motif chemokine ligand 4	solute carrier family 30 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR1 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Identical Protein Binding CCR Chemokine Receptor Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Identical Protein Binding
	Biological Process	Monocyte Chemotaxis Inflammatory Response Immune Response Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Response To Toxic Substance Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Transcription Lymphocyte Chemotaxis Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transport Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Natural Killer Cell Chemotaxis	Response To Zinc Ion Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling	Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		8 interacting genes: ACKR2 CCL3 CCR1 CCR3 CCR5 CCR8 CXCL8 SLC30A2	11 interacting genes: ADAM33 CCL4 CCL4L2 CD99L2 CREB3 KASH5 LMNA LTA PVR SERPING1 TNFRSF12A
Entrez ID		6351	7780
HPRD ID		01657	18057
Ensembl ID		ENSG00000275302	ENSG00000158014
Uniprot IDs		P13236	Q9BRI3
PDB IDs		1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?
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