CLCN5 and MAGI1

Number of citations of the paper that reports this interaction (PubMedID 9169421)
41

Data Source:
HPRD (in vitro)

		CLCN5	MAGI1
Description		chloride voltage-gated channel 5	membrane associated guanylate kinase, WW and PDZ domain containing 1
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Endosome Early Endosome Golgi Apparatus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Endosome Membrane Membrane Apical Part Of Cell	Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Cell Junction Cell Projection Cell Periphery
	Molecular Function	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Solute:proton Antiporter Activity Chloride Ion Binding Identical Protein Binding	Protein Binding ATP Binding Protein C-terminus Binding Alpha-actinin Binding Molecular Adaptor Activity
	Biological Process	Excretion Ion Transmembrane Transport Chloride Transmembrane Transport Proton Transmembrane Transport	Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Protein-containing Complex Assembly
Pathways		Stimuli-sensing channels
Drugs
Diseases		Dent disease, including: Dent disease 1; Dent disease 2; X-linked recessive nephrolithiasis ; Hypophosphatemic rickets; Low-molecular-weight proteinuria with hypercalciuria and nephrocalcinosis
GWAS		Height ( 28552196) Hip circumference adjusted for BMI ( 28552196)	Adolescent idiopathic scoliosis ( 28334814) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Cobalt levels ( 26025379) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Crohn's disease-related phenotypes ( 25557950) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Knee osteoarthritis ( 28916551) Neurociticism ( 29500382) Neuroticism ( 25993607) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 23534349) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		4 interacting genes: CFL1 MAGI1 WWP1 WWP2	24 interacting genes: ACTN4 ADGRB1 AMOT ASIC3 ATN1 CLCN5 CRHR1 CTNNB1 DAG1 GBP2 IGSF5 IL6R LRP2 NET1 RAC1 RASA1 RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2
Entrez ID		1184	9223
HPRD ID		02053	04020
Ensembl ID		ENSG00000171365	ENSG00000151276
Uniprot IDs		A8K4H5 B3KRR2 P51795 V9GYG7	Q96QZ7
PDB IDs		2J9L 2JA3	1WBP 2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU 5N7D 5N7F 5N7G
Enriched GO Terms of Interacting Partners?
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