PTPMT1 and RGS20

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		PTPMT1	RGS20
Description		protein tyrosine phosphatase mitochondrial 1	regulator of G protein signaling 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrial Inner Membrane	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatidylglycerophosphatase Activity	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Cardiolipin Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Regulation Of Intrinsic Apoptotic Signaling Pathway	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Synthesis of PG	G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate ( 29403010) Hypertension ( 27618448) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mean arterial pressure ( 27618448) Mood instability ( 31168069) Neuroticism ( 29255261) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)	Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		16 interacting genes: KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP2-4 KRTAP5-9 KRTAP9-2 MAPK6 MDFI MTUS2 NOTCH2NLA RGS20 SIAH1 TAB1 TRIM27	34 interacting genes: ABHD17A ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 NECTIN3 OSTM1 OTX1 PTGER3 PTPMT1 STMN2 TBC1D16
Entrez ID		114971	8601
HPRD ID		15151	06225
Ensembl ID		ENSG00000110536	ENSG00000147509
Uniprot IDs		Q8WUK0	B3KSW4 H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?