PNMA5 and VPS28

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PNMA5	VPS28
Description		PNMA family member 5	VPS28 subunit of ESCRT-I
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS			Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		32 interacting genes: AP1M1 ARPC4 C11orf49 CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 DDX6 GLIPR2 GORASP2 GRB2 KPNA2 MOAP1 MYO15B NTAQ1 PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 TBC1D22B TNPO2 TTC23 TXNL4B VIM VPS28 ZBTB25 ZFYVE26 ZMYND19	30 interacting genes: ASF1A BLZF1 CARD9 CBX5 CEP57L1 FABP3 GABARAP GLCCI1 GOLGA2 INCA1 MBIP PDCD6IP PNMA5 RASSF5 SAXO1 SKIL SMN1 SMN2 TCF12 TCF4 TRIM27 TRIM54 TSG101 UBA52 UBC USHBP1 VPS37A VPS37B VPS37C VPS52
Entrez ID		114824	51160
HPRD ID		06678	11675
Ensembl ID		ENSG00000198883	ENSG00000160948
Uniprot IDs		Q96PV4	A0A0S2Z5H5 Q548N1 Q9UK41
PDB IDs
Enriched GO Terms of Interacting Partners?
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