CHRNG and CHRNA1

Number of citations of the paper that reports this interaction (PubMedID 7695910)
20

Data Source:
HPRD (in vitro)

		CHRNG	CHRNA1
Description		cholinergic receptor nicotinic gamma subunit	cholinergic receptor nicotinic alpha 1 subunit
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Junction Neuron Projection Synapse Postsynaptic Membrane	Cell Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Cell Surface Cell Junction Neuromuscular Junction Neuron Projection Synapse Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Protein Binding Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Acetylcholine Binding	Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Muscle Contraction Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Ion Transmembrane Transport Response To Nicotine Regulation Of Membrane Potential Nervous System Process Excitatory Postsynaptic Potential	Skeletal Muscle Contraction Cation Transport Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Neuromuscular Junction Development Neuronal Action Potential Ion Transmembrane Transport Response To Nicotine Regulation Of Membrane Potential Muscle Cell Cellular Homeostasis Skeletal Muscle Tissue Growth Nervous System Process Musculoskeletal Movement Neuromuscular Process Excitatory Postsynaptic Potential Neuron Cellular Homeostasis
Pathways		Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
Drugs		Galantamine	Galantamine Agmatine
Diseases		Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)	Congenital myasthenic syndrome Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
GWAS		Refractive error ( 23396134)	Atrial fibrillation ( 29892015)
Interacting Genes		11 interacting genes: ADAMTSL4 CHRNA1 KRT31 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MDFI MEOX2 NOTCH2NLA SPRY2	4 interacting genes: CHRND CHRNE CHRNG ITGA7
Entrez ID		1146	1134
HPRD ID		00009	00007
Ensembl ID		ENSG00000196811	ENSG00000138435
Uniprot IDs		P07510	P02708 Q53SH4
PDB IDs			1Y5P 1Y5T 1Y6C 4ZJS 5HBT
Enriched GO Terms of Interacting Partners?
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