SYNPO and MAGI1

Number of citations of the paper that reports this interaction (PubMedID 12042308)
36

Data Source:
HPRD (in vivo, in vitro)

		SYNPO	MAGI1
Description		synaptopodin	membrane associated guanylate kinase, WW and PDZ domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytosol Bicellular Tight Junction Postsynaptic Density Actin Cytoskeleton Z Disc Dendritic Spine Perikaryon Spine Apparatus Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Cell Junction Cell Projection Cell Periphery
	Molecular Function	Actin Binding Protein Binding	Protein Binding ATP Binding Protein C-terminus Binding Alpha-actinin Binding Molecular Adaptor Activity
	Biological Process	Visual Learning Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Modification Of Dendritic Spine Postsynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Postsynaptic Cytosolic Calcium Concentration Spine Apparatus Assembly	Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Protein-containing Complex Assembly
Pathways
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401)	Adolescent idiopathic scoliosis ( 28334814) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Cobalt levels ( 26025379) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Crohn's disease-related phenotypes ( 25557950) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Knee osteoarthritis ( 28916551) Neurociticism ( 29500382) Neuroticism ( 25993607) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 23534349) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		7 interacting genes: G3BP1 MAGI1 NCK1 NCK2 NONO YWHAG YWHAZ	24 interacting genes: ACTN4 ADGRB1 AMOT ASIC3 ATN1 CLCN5 CRHR1 CTNNB1 DAG1 GBP2 IGSF5 IL6R LRP2 NET1 RAC1 RASA1 RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2
Entrez ID		11346	9223
HPRD ID		12179	04020
Ensembl ID		ENSG00000171992	ENSG00000151276
Uniprot IDs		Q8N3V7	Q96QZ7
PDB IDs			1WBP 2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU 5N7D 5N7F 5N7G
Enriched GO Terms of Interacting Partners?
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