SYNPO and G3BP1

		SYNPO	G3BP1
Description		synaptopodin	G3BP stress granule assembly factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytosol Bicellular Tight Junction Postsynaptic Density Actin Cytoskeleton Z Disc Dendritic Spine Perikaryon Spine Apparatus Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Nucleus Cytoplasm Cytosol Focal Adhesion Cytoplasmic Stress Granule Perikaryon Ribonucleoprotein Complex
	Molecular Function	Actin Binding Protein Binding	DNA Binding DNA Helicase Activity RNA Binding RNA Helicase Activity MRNA Binding Endonuclease Activity Protein Binding ATP Binding
	Biological Process	Visual Learning Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Long-term Neuronal Synaptic Plasticity Modification Of Dendritic Spine Postsynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Postsynaptic Cytosolic Calcium Concentration Spine Apparatus Assembly	Ras Protein Signal Transduction Viral Process DNA Duplex Unwinding Type I Interferon Production Stress Granule Assembly Innate Immune Response Defense Response To Virus Positive Regulation Of Stress Granule Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401)
Interacting Genes		7 interacting genes: G3BP1 MAGI1 NCK1 NCK2 NONO YWHAG YWHAZ	16 interacting genes: APP CSK DNAH1 DTX1 EPHA8 FBXO25 HAND1 HDAC6 HMGXB3 IL7R LCK PIN1 PPIA RASA1 SYNPO USP10
Entrez ID		11346	10146
HPRD ID		12179	06569
Ensembl ID		ENSG00000171992	ENSG00000145907
Uniprot IDs		Q8N3V7	Q13283 Q5U0Q1 Q6ZP53
PDB IDs			3Q90 4FCJ 4FCM 4IIA 5FW5
Enriched GO Terms of Interacting Partners?
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