GLCCI1 and VPS28

Number of citations of the paper that reports this interaction (PubMedID 11591653)
41

Data Source:
HPRD (in vitro, in vivo)

		GLCCI1	VPS28
Description		glucocorticoid induced 1	VPS28 subunit of ESCRT-I
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	ESCRT I Complex Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome
	Molecular Function		Protein Binding Ubiquitin Binding Protein-containing Complex Binding
	Biological Process		Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Protein Ubiquitination Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Protein Catabolic Process Intracellular Transport Of Virus Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive function ( 24684796) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Height ( 28552196 31562340) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 23836780) Macular thickness ( 30535121) Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event) ( 28753643) Night sleep phenotypes ( 27126917) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Weight ( 28552196)	Blood metabolite levels ( 26401656) Educational attainment ( 25201988)
Interacting Genes		1 interacting genes: VPS28	30 interacting genes: ASF1A BLZF1 CARD9 CBX5 CEP57L1 FABP3 GABARAP GLCCI1 GOLGA2 INCA1 MBIP PDCD6IP PNMA5 RASSF5 SAXO1 SKIL SMN1 SMN2 TCF12 TCF4 TRIM27 TRIM54 TSG101 UBA52 UBC USHBP1 VPS37A VPS37B VPS37C VPS52
Entrez ID		113263	51160
HPRD ID		17043	11675
Ensembl ID		ENSG00000106415	ENSG00000160948
Uniprot IDs		Q86VQ1	A0A0S2Z5H5 Q548N1 Q9UK41
PDB IDs
Enriched GO Terms of Interacting Partners?
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