COPE and TMED10

Number of citations of the paper that reports this interaction (PubMedID 9751720)
25

Data Source:
BioGRID (pull down)

		COPE	TMED10
Description		COPI coat complex subunit epsilon	transmembrane p24 trafficking protein 10
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol COPI Vesicle Coat Transport Vesicle	Golgi Membrane Cell Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Secretory Granule Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Gamma-secretase Complex
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Syntaxin Binding Protein-containing Complex Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Protein Transport	Kidney Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Cargo Loading Into Vesicle COPI-coated Vesicle Budding Response To Alkaloid Regulated Exocytosis Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Regulation Of Amyloid-beta Formation
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Height ( 19343178)
Interacting Genes		12 interacting genes: ARF1 COPA COPB1 COPB2 COPG1 COPG2 EFHC2 GDF15 RCHY1 SCYL1 TMED10 WBP2	18 interacting genes: APH1A ARCN1 ARF1 COPA COPB1 COPB2 COPE COPG1 COPG2 COPZ1 DHODH FBXO7 GORASP2 NCSTN NPC2 PSENEN SEC23B TMED2
Entrez ID		11316	10972
HPRD ID		06089	12013
Ensembl ID		ENSG00000105669	ENSG00000170348
Uniprot IDs		M0QXB4 O14579	A0A024R6I3 P49755
PDB IDs		6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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