PDCD10 and CHMP5

Number of citations of the paper that reports this interaction (PubMedID 16730941)
60

Data Source:
HPRD (two hybrid)

		PDCD10	CHMP5
Description		programmed cell death 10	charged multivesicular body protein 5
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GO Annotations	Cellular Component	Golgi Membrane Cell Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome	Cell Nucleus Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding	Protein Binding Cadherin Binding
	Biological Process	Angiogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Leukemia Inhibitory Factor	Regulation Of Receptor Recycling Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases		Cerebral cavernous malformation
GWAS		Fast beta electroencephalogram ( 28070124)	Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		5 interacting genes: CHMP5 RHOA STK24 STK25 STK26	17 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 NUP98 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91
Entrez ID		11235	51510
HPRD ID		10141	15408
Ensembl ID		ENSG00000114209	ENSG00000086065
Uniprot IDs		C9J363 Q9BUL8	Q9NZZ3
PDB IDs		3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH 4TVQ	2LXM 3ULY 3UM0 3UM1 3UM2 4TXR
Enriched GO Terms of Interacting Partners?
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