SEC63 and SEC61B

Number of citations of the paper that reports this interaction (PubMedID 10799540)
54

Data Source:
HPRD (in vitro)

		SEC63	SEC61B
Description		SEC63 homolog, protein translocation regulator	SEC61 translocon subunit beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Sec62/Sec63 Complex	Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Endoplasmic Reticulum Sec Complex
	Molecular Function	RNA Binding Protein Binding Protein Transmembrane Transporter Activity Signaling Receptor Activity	RNA Binding ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Epidermal Growth Factor Binding
	Biological Process	Liver Development Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Nitrogen Compound Metabolic Process Multicellular Organism Aging Posttranslational Protein Targeting To Membrane, Translocation	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Posttranslational Protein Targeting To Membrane, Translocation
Pathways			ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Polycystic liver disease
GWAS			Callous-unemotional behaviour ( 23874384) Gestational age at birth (maternal effect) ( 28877031) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		4 interacting genes: HSPA5 MEOX2 SEC61B SEC62	11 interacting genes: APOB ARL6 ATP13A2 BAG6 GET3 GET4 SEC63 SERP1 SPC25 TRAM1 UBL4A
Entrez ID		11231	10952
HPRD ID		09783	06715
Ensembl ID		ENSG00000025796	ENSG00000106803
Uniprot IDs		A0A0S2Z5M1 Q9UGP8	P60468
PDB IDs
Enriched GO Terms of Interacting Partners?
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