STRAP and SNRPE

Number of citations of the paper that reports this interaction (PubMedID 15848170)
31

Data Source:
HPRD (in vitro)

		STRAP	SNRPE
Description		serine/threonine kinase receptor associated protein	small nuclear ribonucleoprotein polypeptide E
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Signaling Receptor Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal SnRNP Assembly Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process Hair Cycle Import Into Nucleus
Pathways		Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS			Male-pattern baldness ( 28196072) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		24 interacting genes: CHEK2 GEMIN6 GEMIN7 MAP1B MTRES1 NXF1 PBLD PDPK1 RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO4 TGFBR1 TGFBR2	18 interacting genes: DDX20 GEMIN5 GEMIN6 GEMIN7 HRAS IL7R LSM2 LSM3 LSM4 LSM5 SMN1 SMN2 SNRPD3 SNRPF SNRPG STRAP WDR77 YWHAQ
Entrez ID		11171	6635
HPRD ID		05816	00548
Ensembl ID		ENSG00000023734	ENSG00000182004
Uniprot IDs		B0AZV0 Q9Y3F4	P62304
PDB IDs			3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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