AP4S1 and GTF2I

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		AP4S1	GTF2I
Description		adaptor related protein complex 4 subunit sigma 1	general transcription factor IIi
Image		No pdb structure
GO Annotations	Cellular Component	AP-4 Adaptor Complex Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Cell Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function		DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Protein Targeting Protein Localization Vesicle-mediated Transport	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Angiogenesis Negative Regulation Of Cytosolic Calcium Ion Concentration
Pathways		Lysosome Vesicle Biogenesis
Drugs
Diseases		Cerebral palsy
GWAS			Atrial fibrillation ( 30061737 29892015) C-reactive protein levels ( 30388399) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 30598549) Menarche (age at onset) ( 25231870) SjÃ¶gren's syndrome ( 24097066 27503288) Systemic lupus erythematosus ( 28714469)
Interacting Genes		5 interacting genes: AFP APP GRB2 GTF2I TEAD3	39 interacting genes: AP2B1 AP4S1 ATF6 BCL2L11 BTK C4BPA CALM1 DNMT3L DPY30 GCC1 HDAC3 JAK2 LSM8 MAP3K3 MAPK12 MAPK3 MTUS2 MYC NFKB2 PIAS2 PJA1 POU2AF1 PRKG1 PRRX1 SLU7 SMAD2 SNRPN SRC SRF STAT1 STAT3 TAB2 TRAF6 UBC UBE2I USF1 YY1 ZBTB17 ZMYM3
Entrez ID		11154	2969
HPRD ID		06257	03399
Ensembl ID		ENSG00000100478	ENSG00000263001
Uniprot IDs		Q9Y587	A8K9W7 P78347 Q499G6 X5D2J9 X5D939 X5DNP5 X5DR09
PDB IDs			2D9B 2DN4 2ED2 2EJE
Enriched GO Terms of Interacting Partners?
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