AP4S1 and AFP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

		AP4S1	AFP
Description		adaptor related protein complex 4 subunit sigma 1	alpha fetoprotein
Image		No pdb structure
GO Annotations	Cellular Component	AP-4 Adaptor Complex Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Extracellular Space Cytoplasm Endoplasmic Reticulum Lumen
	Molecular Function		Fatty Acid Binding Protein Binding Zinc Ion Binding
	Biological Process	Protein Targeting Protein Localization Vesicle-mediated Transport	Ovulation From Ovarian Follicle Transport Progesterone Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process SMAD Protein Signal Transduction
Pathways		Lysosome Vesicle Biogenesis	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases		Cerebral palsy
GWAS			Blood protein levels ( 30072576) Prostate cancer ( 23535732) Tumor biomarkers ( 23300138)
Interacting Genes		5 interacting genes: AFP APP GRB2 GTF2I TEAD3	10 interacting genes: AP4S1 CCR5 EHD4 GNB1 MED27 PHB2 PIDD1 PSMB7 SGSM2 XIAP
Entrez ID		11154	174
HPRD ID		06257	00074
Ensembl ID		ENSG00000100478	ENSG00000081051
Uniprot IDs		Q9Y587	P02771
PDB IDs			3MRK
Enriched GO Terms of Interacting Partners?
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