HSF2BP and HSF2

Number of citations of the paper that reports this interaction (PubMedID 9651507)
3

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		HSF2BP	HSF2
Description		heat shock transcription factor 2 binding protein	heat shock transcription factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Transcription By RNA Polymerase II Spermatogenesis	Transcription By RNA Polymerase II Spermatogenesis Cellular Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Heat Stress
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Eosinophilic esophagitis ( 25017104) Mean corpuscular volume ( 27863252) Plasma anti-thyroid peroxidase levels ( 29678681) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 30578418)	Atrial fibrillation ( 28416822 30061737 29892015) Disease progression in age-related macular degeneration ( 29346644) Lymphocyte counts ( 27863252) Optic cup area ( 25631615 31798171 28073927) Optic disc size ( 31809533) Pulse pressure ( 30224653 27841878) Subcutaneous adipose tissue ( 26480920) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Vertical cup-disc ratio ( 31798171 25241763) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Word reading ( 30741946)
Interacting Genes		4 interacting genes: CDC73 HSF2 UBE2I UPF2	15 interacting genes: CDC20 CDC27 CUL3 HSF1 HSF2BP MTUS2 NCAPG NUP62 PCGF2 PPP2R1A SUMO2 SUMO3 TPM3 UBE2I WDR5
Entrez ID		11077	3298
HPRD ID		05186	00779
Ensembl ID		ENSG00000160207	ENSG00000025156
Uniprot IDs		O75031 Q6IAT7	Q03933 Q9BS48
PDB IDs			5D8K 5D8L 5HDK
Enriched GO Terms of Interacting Partners?
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