SOX30 and FLI1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SOX30	FLI1
Description		SRY-box transcription factor 30	Fli-1 proto-oncogene, ETS transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm Chromocenter	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Nuclear Body
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Beta-catenin Binding Sequence-specific DNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Hemostasis Blood Circulation Animal Organ Morphogenesis Cell Differentiation Megakaryocyte Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Transcriptional regulation of granulopoiesis
Drugs
Diseases			Ewing's sarcoma
GWAS		Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)	Albumin-globulin ratio ( 29403010) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Corneal astigmatism ( 30306274) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Heel bone mineral density ( 30598549) Height ( 20881960 31562340) Left ventricular obstructive tract defect (inherited effect) ( 28468790) Myopia (pathological) ( 23049088) Non-albumin protein levels ( 29403010) Platelet count ( 27863252) Plateletcrit ( 27863252) Rheumatoid arthritis ( 22446963) Rheumatoid arthritis (ACPA-positive) ( 24532676) Systemic lupus erythematosus ( 27399966 26502338) Vitiligo ( 27723757)
Interacting Genes		18 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FLI1 GNAI3 GP2 KIFC3 MRPS5 NME1 NUDT3 PAXIP1 TRAF2	18 interacting genes: BRCA1 CTBP2 ELK1 ERG ETV6 EWSR1 GATA1 KLF1 PIAS1 PIAS2 PRKCD SIAH1 SMAD3 SMAD9 SOX30 SRF TDP2 UBE2I
Entrez ID		11063	2313
HPRD ID		09461	01901
Ensembl ID		ENSG00000039600	ENSG00000151702
Uniprot IDs		B4DXW7 O94993	A0A024R3K4 A0A024R3M5 A0A024R3N6 Q01543
PDB IDs			1FLI 1X66 2YTU 5E8G 5E8I 5JVT
Enriched GO Terms of Interacting Partners?
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