KDELR2 and TTYH2

Number of citations of the paper that reports this interaction (PubMedID 28205554)
32

Data Source:
BioGRID (fluorescent resonance energy transfer)

		KDELR2	TTYH2
Description		KDEL endoplasmic reticulum protein retention receptor 2	tweety family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cis-Golgi Network Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Membrane	Plasma Membrane Chloride Channel Complex
	Molecular Function	KDEL Sequence Binding ER Retention Sequence Binding	Intracellular Calcium Activated Chloride Channel Activity Protein Binding Volume-sensitive Chloride Channel Activity
	Biological Process	Protein Retention In ER Lumen ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Protein Transport	Chloride Transmembrane Transport
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Stimuli-sensing channels
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Body mass index ( 26426971) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908) Irritable bowel syndrome ( 25248455) Lymphocyte percentage of white cells ( 27863252) Mean platelet volume ( 27863252) Monocyte count ( 29403010 27863252) Monocyte percentage of white cells ( 27863252) Neutrophil percentage of white cells ( 27863252) Ulcerative colitis ( 28067908)	Systolic blood pressure (cigarette smoking interaction) ( 26752167)
Interacting Genes		22 interacting genes: AKT1 BECN1 CCND2 CD44 CDK4 CDK6 CDKN2B EPHA2 ERBB2 FGFR4 GRM1 IGF1R KAT2A LATS2 MAP2K3 MET MYC NF2 PDGFRA RASSF1 STK11 TTYH2	12 interacting genes: CCND2 CDKN2B ERBB2 FGFR4 GRM1 IGF1R IKBKG KAT2A KDELR2 NEDD4 NF2 PDGFRA
Entrez ID		11014	94015
HPRD ID		06598	16394
Ensembl ID		ENSG00000136240	ENSG00000141540
Uniprot IDs		A0A024QZT7 P33947	B4DKD1 Q8N3U8 Q9BSA4
PDB IDs
Enriched GO Terms of Interacting Partners?
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