IL24 and BAG4

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		IL24	BAG4
Description		interleukin 24	BAG cochaperone 4
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Cytosol Plasma Membrane
	Molecular Function	Cytokine Activity Protein Binding	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process	Apoptotic Process Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Migration Wound Healing Serine Phosphorylation Of STAT Protein Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-4	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Ruffle Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Pathways		Interleukin-20 family signaling	Regulation of HSF1-mediated heat shock response Signaling by FGFR1 in disease TNF signaling Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 29483656)
Interacting Genes		25 interacting genes: AKT1 APC ATM BAG4 CASP8 CCR5 CLU DCD ESR2 FBXW7 HMMR HRAS IL20RA KRAS LSP1 NOTCH2 PALB2 PARP1 PIK3CA PTEN RAD51 RARG RB1CC1 RIPK3 SMAD4	38 interacting genes: APOBEC1 ATAD2 BAP1 BCAS3 BCL2 BEX1 CASZ1 CCL5 DIRAS3 EPSTI1 ERRFI1 GLCE GRAP2 HSPA1A HSPA8 IL13RA2 IL24 ITIH5 KLK5 KLK7 KLK9 LRATD2 LYPD3 MRC2 MTA3 NAT2 PDLIM2 PLAT PRDM14 RASL10B RHOBTB2 RNF20 RPL22 SCGB3A1 TBC1D7 THRSP TNFRSF1A TNFRSF25
Entrez ID		11009	9530
HPRD ID		04995	04861
Ensembl ID		ENSG00000162892	ENSG00000156735
Uniprot IDs		Q13007	O95429
PDB IDs		6DF3 6GG1	1M62 1M7K
Enriched GO Terms of Interacting Partners?
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