SF3B2 and U2AF1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		SF3B2	U2AF1
Description		splicing factor 3b subunit 2	U2 small nuclear RNA auxiliary factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Viral Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Metabolite levels ( 23823483)	Blood and toenail selenium levels ( 25343990)
Interacting Genes		31 interacting genes: AKAP9 APBB1 APP C7orf25 C8orf33 CASK CSNK2A1 ECPAS ERG FMR1 FRA10AC1 HNRNPC KDM1A LSM2 LSM3 PCBP2 PRC1 PRPF40A RBM10 RBM7 RBM8A SF3B4 SMAD3 SNRNP200 TCERG1 THOC1 TOE1 TOPBP1 TTC14 U2AF1 ZCCHC10	38 interacting genes: AP2B1 CHERP CIR1 CLK2 DHX38 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 MAP1B MFAP1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRPD1 SRPK1 SRSF1 SRSF2 SUV39H1 TOE1 U2AF2 VEGFA ZCCHC10 ZRANB2 ZRSR2
Entrez ID		10992	7307
HPRD ID		10410	01871
Ensembl ID		ENSG00000087365	ENSG00000160201
Uniprot IDs		Q13435	P0DN76 Q01081 Q7Z780
PDB IDs		2DO5 5Z56 5Z57 5Z58 6AH0 6FF4 6FF7 6QX9	1JMT
Enriched GO Terms of Interacting Partners?
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