COPS5 and NR4A2

  • Number of citations of the paper that reports this interaction (PubMedID 15604093)
  • 54

COPS5

NR4A2

Description COP9 signalosome subunit 5 nuclear receptor subfamily 4 group A member 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at voice drop ( 27182965)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Depression ( 29700475)
  • Leisure-time exercise behaviour ( 30102679)
  • Leisure-time exercise behaviour (age-stratified) ( 30102679)
  • Lung function (FEV1/FVC) ( 30061609)
  • Menarche (age at onset) ( 21102462 25231870)
  • Response to statin therapy ( 20339536)
Interacting Genes 93 interacting genes: APCS ARFGAP1 ATM ATRN BCL2L14 BCL3 BRD4 BRSK2 CACNA1C CD93 CDKN1B CENPT CHUK COPS2 COPS3 COPS4 COPS6 COPS7A COPS8 COPS9 CUL1 CUL2 CUL5 DDB1 DDO ERN1 ERRFI1 ESR1 F2RL1 GFER GFI1B GPS1 HAND2 HIF1A HNF4A HNF4G HTR6 ITGB2 JUN JUND LASP1 MAP2K2 MAP3K11 MAP3K3 MAP3K7 MAP4K3 MAP4K5 MAPK14 MAPRE1 MAX MDC1 MDM2 MEF2C MEF2D MIF MTRES1 MYG1 NCOA1 NEDD8 NFKB1 NR4A2 NR4A3 OPRM1 PEA15 PGR PLAC8 PPARG PPOX PPP1CC PRDX2 PRKD1 PTGS2 RAD1 RAD9A RNF139 RORA S100A7 SHANK3 SHISA5 SMAD2 SMAD4 SMAD5 SPP1 SREBF2 TOP2A TP53 TXN TYK2 UCHL1 USP14 VTN WNK1 YWHAG 13 interacting genes: BAZ1B CDKN1C CDKN2D COPS5 PIAS4 PPARG RPS6KA1 RXRA RXRB SMARCA2 SMARCA4 TCEAL5 VHL
Entrez ID 10987 4929
HPRD ID 06888 03493
Ensembl ID ENSG00000121022 ENSG00000153234
Uniprot IDs A0A024R7W9 Q92905 F1D8N6 F1DAL2 P43354 Q53EL4
PDB IDs 4D10 4D18 4F7O 4WSN 5JOG 5JOH 5M5Q 6R6H 6R7F 6R7H 6R7I 1OVL 5Y41 5YD6 6DDA 6L6L 6L6Q
Enriched GO Terms of Interacting Partners?
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