NR4A2 and PIAS4

  • Number of citations of the paper that reports this interaction (PubMedID 14559918)
  • 18
  • Data Source:
  • HPRD (two hybrid, in vitro, in vivo)

NR4A2

PIAS4

Description nuclear receptor subfamily 4 group A member 2 protein inhibitor of activated STAT 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at voice drop ( 27182965)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Depression ( 29700475)
  • Leisure-time exercise behaviour ( 30102679)
  • Leisure-time exercise behaviour (age-stratified) ( 30102679)
  • Lung function (FEV1/FVC) ( 30061609)
  • Menarche (age at onset) ( 21102462 25231870)
  • Response to statin therapy ( 20339536)
  • Chronic lymphocytic leukemia ( 28165464)
Interacting Genes 13 interacting genes: BAZ1B CDKN1C CDKN2D COPS5 PIAS4 PPARG RPS6KA1 RXRA RXRB SMARCA2 SMARCA4 TCEAL5 VHL 82 interacting genes: ACTN1 ALDOA AR AREL1 BARD1 BRCA1 BTAF1 CALCOCO2 CEBPD CHD3 CLK1 COIL ESRRA FTH1 GADD45G HDAC1 HDAC2 HNF4A HNRNPUL1 HTT IL15RA IMMT IMPDH2 IRF3 IRF7 KNTC1 KPNB1 KRT18 LAMP2 LEF1 LRIF1 MAGEH1 MAP1LC3A MDC1 MPRIP NEFL NR4A2 OAZ1 OPTN PARP1 PDE4A PDE4D PDE4DIP PHF11 PHGDH PIAS1 PIAS2 PLAG1 PRKCZ PRPF40A PTN RIF1 SATB1 SERBP1 SERPINA5 SETDB1 SH3GL3 SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SNAI2 SNIP1 SUMO1 SUMO2 SUMO3 TADA3 TCERG1 TICAM1 TOP2A TP53 TRIM27 TRIM32 UBE2I UBE2K VHL VIM ZHX1 ZNF512B ZW10
Entrez ID 4929 51588
HPRD ID 03493 06910
Ensembl ID ENSG00000153234 ENSG00000105229
Uniprot IDs F1D8N6 F1DAL2 P43354 Q53EL4 B3KMR4 Q8N2W9
PDB IDs 1OVL 5Y41 5YD6 6DDA 6L6L 6L6Q
Enriched GO Terms of Interacting Partners?
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