CPSF4 and FIP1L1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		CPSF4	FIP1L1
Description		cleavage and polyadenylation specific factor 4	factor interacting with PAPOLA and CPSF1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Intracellular Membrane-bounded Organelle	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Export From Nucleus MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing Pre-mRNA Cleavage Required For Polyadenylation	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Export From Nucleus MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript Inhibition of Host mRNA Processing and RNA Silencing tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944) Tacrolimus trough concentration in kidney transplant patients ( 29160300)	DNA methylation (variation) ( 23725790) Red blood cell count ( 28453575) Serum VEGFR2 concentration ( 25411163)
Interacting Genes		5 interacting genes: CREBBP FIP1L1 MARK3 MEOX2 SLC12A9	14 interacting genes: APP CPSF4 CSNK2A1 GOLGA2 HMGB1 LIG4 NAA10 PAPOLA PRMT2 PRMT6 SGTA SRPK2 WWOX ZMYND19
Entrez ID		10898	81608
HPRD ID		04338	09646
Ensembl ID		ENSG00000160917	ENSG00000145216
Uniprot IDs		B7Z7B0 O95639	Q6UN15
PDB IDs		2D9N 2RHK 6DNH 6FBS 6FUW 6URG 6URO
Enriched GO Terms of Interacting Partners?
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