FIP1L1 and PRMT2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		FIP1L1	PRMT2
Description		factor interacting with PAPOLA and CPSF1	protein arginine methyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding	Transcription Coactivator Activity Protein Binding Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Estrogen Receptor Binding Progesterone Receptor Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Protein Homodimerization Activity Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Export From Nucleus MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation	Protein Methylation Signal Transduction Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Arginine Methylation Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Developmental Cell Growth Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
Drugs
Diseases
GWAS		DNA methylation (variation) ( 23725790) Red blood cell count ( 28453575) Serum VEGFR2 concentration ( 25411163)	Diverticular disease ( 30177863)
Interacting Genes		14 interacting genes: APP CPSF4 CSNK2A1 GOLGA2 HMGB1 LIG4 NAA10 PAPOLA PRMT2 PRMT6 SGTA SRPK2 WWOX ZMYND19	23 interacting genes: BAG6 CBLB CHEK2 CPSF7 DMRTB1 ESR1 ESR2 FIP1L1 HNRNPA1 HNRNPUL1 NCOA1 NCOA6 PGR PRRC2A PSMB3 RB1 RBM12 RIPK2 RXRA SPAG8 THRB WASL ZNF341
Entrez ID		81608	3275
HPRD ID		09646	09060
Ensembl ID		ENSG00000145216	ENSG00000160310
Uniprot IDs		Q6UN15	A0A0S2Z3N3 P55345
PDB IDs			1X2P
Enriched GO Terms of Interacting Partners?
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