SEPTIN9 and PTPRF

Number of citations of the paper that reports this interaction (PubMedID 25458010)
15

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SEPTIN9	PTPRF
Description		septin 9	protein tyrosine phosphatase receptor type F
Image
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Microtubule Axoneme Septin Ring Actin Cytoskeleton Microtubule Cytoskeleton Septin Complex Cell Division Site Perinuclear Region Of Cytoplasm Non-motile Cilium	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Neuronal Cell Body Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Heparin Binding Chondroitin Sulfate Proteoglycan Binding Protein-containing Complex Binding Cell Adhesion Molecule Binding
	Biological Process	Cellular Protein Localization Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly	Protein Dephosphorylation Cell Adhesion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Migration Neuron Projection Regeneration Peptidyl-tyrosine Dephosphorylation Regulation Of Axon Regeneration Synaptic Membrane Adhesion Negative Regulation Of Receptor Binding
Pathways			Receptor-type tyrosine-protein phosphatases Synaptic adhesion-like molecules
Drugs
Diseases		Hereditary neuralgic amyotrophy (HNA); Hereditary brachial plexus neuropathy
GWAS			Adventurousness ( 30643258) Amyotrophic lateral sclerosis (age of onset) ( 22959728) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 30478444) Attention deficit hyperactivity disorder or cannabis use ( 30610198) Autism spectrum disorder or schizophrenia ( 28540026) Coffee consumption ( 31046077) Cognitive ability (MTAG) ( 29186694) Educational attainment ( 27046643) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Household income (MTAG) ( 31844048) Intake of total sugars ( 31005972) Intelligence (MTAG) ( 29326435) Schizophrenia ( 28991256 25056061 29483656 30285260) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Stroke ( 29531354) Urate levels ( 31578528)
Interacting Genes		14 interacting genes: APP HIF1A HNRNPD IKBKG LINC00839 NEDD4 PTPRF RAB10 SEPTIN1 SEPTIN11 SEPTIN2 SEPTIN6 SEPTIN7 STK11	55 interacting genes: ACAT1 ACTB ARHGEF11 ARHGEF12 ARHGEF2 ATP5F1A BCAR1 CAV1 CBR1 CDH1 CREBBP CTNNB1 DEPDC1B DIAPH1 EEF1A1 EEF1G FRS2 FYN GALNT1 GAPDH GPC4 HSP90AA1 HSPA1A HSPA1L HSPA5 HSPA8 HSPA9 INSR IRS1 IRS2 JUP LACTB LCK LDHA LDHB NID1 PPFIA1 PPFIA2 PPFIA3 PRPF40A PTPRA PTPRD RAP1GDS1 RET RHOA ROCK2 SEMG1 SEMG2 SEPTIN9 SKIL SOWAHC TRIO TUBA1B TUBB4B ZNF512B
Entrez ID		10801	5792
HPRD ID		10360	01552
Ensembl ID		ENSG00000184640	ENSG00000142949
Uniprot IDs		A0A0S2Z5A5 Q9UHD8	G1UI20 P10586
PDB IDs		4YQF 5CYO 5CYP	1LAR 2DJU 2DN7 2EDX 2EDY 2YD5 2YD8 4N5U
Enriched GO Terms of Interacting Partners?
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