PTPRF and RET

  • Number of citations of the paper that reports this interaction (PubMedID 11121408)
  • 7

PTPRF

RET

Description protein tyrosine phosphatase receptor type F ret proto-oncogene
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 30478444)
  • Attention deficit hyperactivity disorder or cannabis use ( 30610198)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Coffee consumption ( 31046077)
  • Cognitive ability (MTAG) ( 29186694)
  • Educational attainment ( 27046643)
  • General cognitive ability ( 29844566)
  • General risk tolerance (MTAG) ( 30643258)
  • Household income (MTAG) ( 31844048)
  • Intake of total sugars ( 31005972)
  • Intelligence (MTAG) ( 29326435)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Smoking initiation ( 30617275)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Stroke ( 29531354)
  • Urate levels ( 31578528)
Interacting Genes 55 interacting genes: ACAT1 ACTB ARHGEF11 ARHGEF12 ARHGEF2 ATP5F1A BCAR1 CAV1 CBR1 CDH1 CREBBP CTNNB1 DEPDC1B DIAPH1 EEF1A1 EEF1G FRS2 FYN GALNT1 GAPDH GPC4 HSP90AA1 HSPA1A HSPA1L HSPA5 HSPA8 HSPA9 INSR IRS1 IRS2 JUP LACTB LCK LDHA LDHB NID1 PPFIA1 PPFIA2 PPFIA3 PRPF40A PTPRA PTPRD RAP1GDS1 RET RHOA ROCK2 SEMG1 SEMG2 SEPTIN9 SKIL SOWAHC TRIO TUBA1B TUBB4B ZNF512B 44 interacting genes: AKAP5 CBL CBLB CRK CTNNB1 DOK1 DOK2 DOK3 DOK4 DOK5 DOK6 DUSP26 ERBB2 FBXO7 FRS2 GAB1 GDNF GFRA1 GRB10 GRB2 GRB7 IKBKG LRRK1 MAPK1 MAPK14 MAPK3 MAPK8 NEDD4 NOTCH2NLA NOTCH3 NRTN PDLIM7 PIK3R1 PLCG1 PRKAR2A PTK2 PTPN11 PTPRF PTPRR SHC1 SHC3 SHC4 SRC STAT3
Entrez ID 5792 5979
HPRD ID 01552 01266
Ensembl ID ENSG00000142949 ENSG00000165731
Uniprot IDs G1UI20 P10586 A0A024R7T2 P07949
PDB IDs 1LAR 2DJU 2DN7 2EDX 2EDY 2YD5 2YD8 4N5U 1XPD 2IVS 2IVT 2IVU 2IVV 2X2K 2X2L 2X2M 2X2U 4CKI 4CKJ 4UX8 5AMN 5FM2 5FM3 6FEK 6GL7 6NE7 6NEC 6NJA 6Q2J 6Q2N 6Q2O 6Q2R 6Q2S
Enriched GO Terms of Interacting Partners?
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