NFAT5 and NUTF2

		NFAT5	NUTF2
Description		nuclear factor of activated T cells 5	nuclear transport factor 2
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytosol Nuclear Transcription Factor Complex	Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytosol Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding	Protein Binding Ran GTPase Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Cytokine Production Transcription By RNA Polymerase II Response To Osmotic Stress Signal Transduction Excretion Calcineurin-NFAT Signaling Cascade Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Cytokine Stimulus Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus MRNA Transport Protein Localization To Nuclear Pore Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways
Drugs
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood urea nitrogen levels ( 31152163 29403010) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Chloride levels ( 29403010) Chronic kidney disease ( 29124443) Creatinine levels ( 29124443) Estimated glomerular filtration rate ( 31015462 30604766) Hand grip strength ( 29691431) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Hyperuricemia ( 29124443) Menarche (age at onset) ( 27182965 21102462 25231870) Metabolic syndrome ( 31589552) Pulse pressure ( 28135244 27841878) Self-reported risk-taking behaviour ( 30181555) Serum uric acid levels ( 30993211 29124443) SjÃ¶gren's syndrome ( 28076899) Smoking initiation (ever regular vs never regular) ( 30679032) Sodium levels ( 29403010) Type 2 diabetes ( 30054458 30297969) Urate levels ( 23263486)	Schizophrenia ( 25056061 29483656)
Interacting Genes		4 interacting genes: FOXP3 NUTF2 TBC1D4 TRIM14	13 interacting genes: CANX GLRX2 KPNB1 LUC7L2 NFAT5 NUP153 NUP54 NUP62 PTMA RAN SF3B3 TERF2 WWP2
Entrez ID		10725	10204
HPRD ID		05272	12050
Ensembl ID		ENSG00000102908	ENSG00000102898
Uniprot IDs		A0A024R734 O94916	A0A024R6Y2 P61970
PDB IDs		1IMH	1GY5
Enriched GO Terms of Interacting Partners?
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