GNA13 and MCF2

Number of citations of the paper that reports this interaction (PubMedID 11062019)
4

Data Source:
HPRD (in vivo, in vitro)

		GNA13	MCF2
Description		G protein subunit alpha 13	MCF.2 cell line derived transforming sequence
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Cytosol Heterotrimeric G-protein Complex Plasma Membrane Focal Adhesion Membrane Brush Border Membrane Melanosome Extracellular Exosome	Cytosol Cytoskeleton Membrane
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding D5 Dopamine Receptor Binding Metal Ion Binding	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Branching Involved In Blood Vessel Morphogenesis In Utero Embryonic Development Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Rho Protein Signal Transduction Regulation Of Cell Shape Cell Differentiation Platelet Activation Regulation Of Cell Migration Activation Of Phospholipase D Activity Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction	G Protein-coupled Receptor Signaling Pathway Dendrite Development Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Cellular Response To Leukemia Inhibitory Factor
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events Thromboxane signalling through TP receptor Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)	Axonal growth inhibition (RHOA activation) NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		White matter microstructure (global fractional anisotropy) ( 24736177)	Metabolite levels ( 23823483)
Interacting Genes		31 interacting genes: AIP AKAP3 ARHGEF1 ARHGEF11 ARHGEF12 CDH1 CDH2 CTNNB1 CXCR4 DRD5 EDNRB F2R GNA12 GPR17 MCF2 MTNR1A PPP5C PRKACA PRKCB PRKCD PRKCE PTK2B RDX RGS16 RIC8A S1PR2 S1PR3 S1PR4 TBXA2R TGFBR1 TSHR	8 interacting genes: CDC42 ERCC3 GNA13 GNB1 RHOA RHOG STUB1 TNK2
Entrez ID		10672	4168
HPRD ID		05100	02406
Ensembl ID		ENSG00000120063	ENSG00000101977
Uniprot IDs		A0A024R8M0 Q14344	B2R9S6 P10911
PDB IDs
Enriched GO Terms of Interacting Partners?
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