CELF2 and APOBEC1

Number of citations of the paper that reports this interaction (PubMedID 11577082)
37

Data Source:
HPRD (in vivo, in vitro)

		CELF2	APOBEC1
Description		CUGBP Elav-like family member 2	apolipoprotein B mRNA editing enzyme catalytic subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding MRNA Binding Pre-mRNA Binding	RNA Binding Cytidine Deaminase Activity Cytosine Deaminase Activity Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Domain Specific Binding MRNA 3'-UTR AU-rich Region Binding Ribonucleoprotein Complex Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection RNA Processing Regulation Of Heart Contraction	RNA Processing MRNA Processing Lipid Metabolic Process Triglyceride Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Response To Gamma Radiation Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Regulation Of Cell Proliferation Lipoprotein Biosynthetic Process Lipoprotein Transport Positive Regulation Of Catalytic Activity Response To Ethanol MRNA Stabilization Response To Calcium Ion Defense Response To Virus DNA Cytosine Deamination DNA Demethylation Negative Regulation Of Triglyceride Metabolic Process Negative Regulation Of Methylation-dependent Chromatin Silencing Positive Regulation Of MRNA Modification
Pathways			mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to drug ( 30420678) Allergic rhinitis ( 30013184) Asthma ( 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Breastfeeding duration ( 25475840) Chronic kidney disease ( 31015462) General risk tolerance (MTAG) ( 30643258) Glycemic traits (pleiotropy) ( 31021400) Liver enzyme levels (alanine transaminase) ( 24124411) Liver enzyme levels (aspartate transaminase) ( 24124411) Motion sickness ( 25628336) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653) Urinary albumin-to-creatinine ratio ( 26631737)	Body mass index ( 28552196) Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899)
Interacting Genes		7 interacting genes: A1CF APOBEC1 APP ELAVL1 PCBP1 PTGS2 TRAF3	8 interacting genes: A1CF APOBEC2 BAG4 CELF2 DNAJB11 DND1 KPNA2 SYNCRIP
Entrez ID		10659	339
HPRD ID		03964	02531
Ensembl ID		ENSG00000048740	ENSG00000111701
Uniprot IDs		A0A0J9YX66 A0A0J9YXJ0 A0A1B0GU44 A0A1B0GUN8 B4DDE7 B4DIB6 B4DT00 B4DZ01 E9PC62 O95319	P41238
PDB IDs		2MY7 2MY8 4LJM 4LMZ 4TLQ 5M8I
Enriched GO Terms of Interacting Partners?
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