SPINT2 and CTSB

  • Number of citations of the paper that reports this interaction (PubMedID 16364318)
  • 7
  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

SPINT2

CTSB

Description serine peptidase inhibitor, Kunitz type 2 cathepsin B
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488 28240269)
  • C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • General risk tolerance (MTAG) ( 30643258)
  • Leprosy ( 27976721)
  • Parkinson's disease ( 28892059)
  • Parkinson's disease in GBA mutation carriers ( 31755958)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • Triglyceride levels ( 29083408)
  • Triglycerides ( 30275531)
Interacting Genes 6 interacting genes: APP CTSB HGFAC ITIH2 ITIH3 SUMO4 36 interacting genes: A2M ACAN ADAMTSL4 ANXA2 ANXA7 APOE APP BAG6 BGLAP CDKN1A CST3 CST7 CSTA CSTB CTSD FAM118B HNRNPD HSPB2 IGF1 INS MARCKS MTDH PARP1 PLAU REN RGS2 S100A10 SERPINB13 SLPI SPHK1 SPINT2 SPRY2 SRPX2 STK11 UBQLN4 XRN1
Entrez ID 10653 1508
HPRD ID 05495 00287
Ensembl ID ENSG00000167642 ENSG00000164733
Uniprot IDs A0A140VJV6 O43291 A0A024R374 B4DMY4 P07858 Q5HYG5
PDB IDs 4U32 1CSB 1GMY 1HUC 1PBH 2IPP 2PBH 3AI8 3CBJ 3CBK 3K9M 3PBH 5MBL 5MBM 6AY2
Enriched GO Terms of Interacting Partners?
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