SORBS1 and TENM1

Number of citations of the paper that reports this interaction (PubMedID 15777793)
27

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SORBS1	TENM1
Description		sorbin and SH3 domain containing 1	teneurin transmembrane protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Centrosome Cytosol Insulin Receptor Complex Adherens Junction Zonula Adherens Focal Adhesion Nuclear Matrix Cell-substrate Junction Membrane Raft	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Nuclear Matrix Nuclear Speck Neuron Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Insulin Receptor Binding Protein Binding Cytoskeletal Protein Binding	Heparin Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Muscle Contraction Cell-matrix Adhesion Insulin Receptor Signaling Pathway Cellular Response To Insulin Stimulus Stress Fiber Assembly Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Import Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Lipid Biosynthetic Process Focal Adhesion Assembly Positive Regulation Of Protein Localization To Plasma Membrane	Regulation Of Transcription By RNA Polymerase III Immune Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Neuropeptide Signaling Pathway Nervous System Development Negative Regulation Of Cell Proliferation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAP Kinase Activity Neuron Development Positive Regulation Of Filopodium Assembly Positive Regulation Of Intracellular Protein Transport
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Diabetic nephropathy in type 1 diabetes ( 25476525) Estimated glomerular filtration rate ( 31152163) Obesity-related traits ( 23251661) PR interval ( 30046033) Staphylococcus aureus nasal carriage (persistent) ( 26569114) Suicide risk ( 21041247)
Interacting Genes		25 interacting genes: ABL1 ACTA1 ADAM15 AFDN CBL CDK6 EFNB1 FLOT1 INPPL1 INSM1 INSR KHDRBS1 MAP4K3 PAK2 PGR PILRA PTK2 PXN RPL4 SEMA6A SH2B2 SLC10A3 SRC TENM1 VCL	2 interacting genes: MBD1 SORBS1
Entrez ID		10580	10178
HPRD ID		05587	06669
Ensembl ID		ENSG00000095637	ENSG00000009694
Uniprot IDs		B4DTX5 Q9BX66	B7ZMH4 Q9UKZ4
PDB IDs		2DL3 2ECZ 2LJ0 2LJ1 2MOX 2O2W 2O31 2O9S 2O9V 4LN2 4LNP
Enriched GO Terms of Interacting Partners?
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