NPC2 and SCRN1

		NPC2	SCRN1
Description		NPC intracellular cholesterol transporter 2	secernin 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Nucleus Cytoplasm Nuclear Membrane
	Molecular Function	Protein Binding Cholesterol Binding Enzyme Binding Sterol Binding Intermembrane Cholesterol Transfer Activity	Molecular_function Protein Binding Dipeptidase Activity
	Biological Process	Cholesterol Metabolic Process Response To Virus Phospholipid Transport Sterol Transport Regulation Of Isoprenoid Metabolic Process Cholesterol Transport Intracellular Sterol Transport Intracellular Cholesterol Transport Cholesterol Efflux Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Neutrophil Degranulation Glycolipid Transport	Proteolysis Exocytosis
Pathways		Neutrophil degranulation LDL clearance
Drugs
Diseases		Niemann-Pick type C disease (NPC), including: Niemann-Pick disease, type C1; Niemann-Pick disease, type C2
GWAS		Advanced glycation end-product levels ( 26915486) Blood protein levels ( 29875488) Intraocular pressure ( 31959993)	Obesity-related traits ( 23251661) Psoriasis ( 25854761)
Interacting Genes		19 interacting genes: AREL1 BARD1 BRCA1 CTSW DHDDS ECT2 EIF2B2 EOLA1 ERRFI1 LIG4 PAXIP1 PDIA6 SCNN1A SCRN1 SSR1 TMED10 TRIM14 USP4 VASH1	3 interacting genes: GORASP1 HGS NPC2
Entrez ID		10577	9805
HPRD ID		03008	15304
Ensembl ID		ENSG00000119655	ENSG00000136193
Uniprot IDs		A0A024R6C0 P61916	A0A024RA21 A0A090N7T9 Q12765
PDB IDs		5KWY
Enriched GO Terms of Interacting Partners?
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