IPO7 and H1-0

Number of citations of the paper that reports this interaction (PubMedID 10228156)
87

Data Source:
HPRD (in vitro)

		IPO7	H1-0
Description		importin 7	H1.0 linker histone
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Membrane	Nucleosome Nuclear Chromatin Nucleus Nucleoplasm Nuclear Euchromatin Golgi Apparatus Actin Cytoskeleton Nuclear Body Transcriptional Repressor Complex
	Molecular Function	Transporter Activity Protein Binding Ran GTPase Binding GTPase Regulator Activity Histone Binding SMAD Binding	AT DNA Binding Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding
	Biological Process	Protein Import Into Nucleus Signal Transduction Viral Process Innate Immune Response Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic DNA Fragmentation Nucleosome Assembly Chromatin Silencing Regulation Of Transcription, DNA-templated Nucleosome Positioning Chromosome Condensation Negative Regulation Of Chromatin Silencing Negative Regulation Of DNA Recombination Positive Regulation Of Transcription Regulatory Region DNA Binding
Pathways			Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Interleukin-10 levels ( 22205395)
Interacting Genes		8 interacting genes: AKTIP H1-0 KPNB1 RAN RPL23A RPL5 RPS7 SRP19	21 interacting genes: APP CCNE1 CDK1 CDK2 CDK4 CDK5 FBXO7 GRB2 HPF1 IKBKG IPO5 IPO7 KPNA2 KPNB1 NEDD4L NOA1 PARP1 PARP2 PRKCB RAD51B XBP1
Entrez ID		10527	3005
HPRD ID		09280	00819
Ensembl ID		ENSG00000205339	ENSG00000189060
Uniprot IDs		B3KNG9 O95373	P07305
PDB IDs			6HQ1 6N88 6N89
Enriched GO Terms of Interacting Partners?
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