CAP2 and CFL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CAP2	CFL2
Description		cyclase associated actin cytoskeleton regulatory protein 2	cofilin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Cortical Actin Cytoskeleton	Extracellular Space Cell Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Adenylate Cyclase Binding Identical Protein Binding	Protein Binding Actin Filament Binding
	Biological Process	Cell Morphogenesis Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity Actin Polymerization Or Depolymerization Regulation Of Adenylate Cyclase Activity	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis
Pathways		Role of ABL in ROBO-SLIT signaling
Drugs
Diseases			Nemaline myopathy
GWAS		Height ( 18391951) Mitochondrial DNA levels ( 25240745) QT interval ( 29213071) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)	Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		6 interacting genes: ACTG1 CAP1 CFL2 MT1P3 PRPF40A YWHAE	10 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LIMK1 POT1 SSH1 STK11 ZYG11B
Entrez ID		10486	1073
HPRD ID		10808	03262
Ensembl ID		ENSG00000112186	ENSG00000165410
Uniprot IDs		P40123 Q5JPJ8	Q549N0 Q9Y281
PDB IDs
Enriched GO Terms of Interacting Partners?
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