NXF1 and IMPA1

Number of citations of the paper that reports this interaction (PubMedID 21965294)
9

Data Source:
BioGRID (pull down, pull down)

		NXF1	IMPA1
Description		nuclear RNA export factor 1	inositol monophosphatase 1
Image
GO Annotations	Cellular Component	Transcription Export Complex Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Speck Nuclear Inclusion Body	Cytoplasm Cytosol
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Magnesium Ion Binding Protein Binding Inositol Monophosphate 1-phosphatase Activity Manganese Ion Binding Lithium Ion Binding Identical Protein Binding Protein Homodimerization Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus Viral Process Poly(A)+ MRNA Export From Nucleus	Inositol Metabolic Process Inositol Biosynthetic Process Phosphatidylinositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation
Pathways		Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript	Synthesis of IP2, IP, and Ins in the cytosol
Drugs			Lithium L-Myo-Inositol-1-Phosphate
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Ovarian cancer ( 23535730)
Interacting Genes		54 interacting genes: ALYREF CSNK2A1 DHX9 DVL3 EIF4A3 ELAVL4 ESRRA GFAP HNRNPUL1 IMPA1 IPO11 IPO4 KCTD5 KRT40 LDOC1 LUZP4 MAGOH MAP1A MAP1B MARK2 MID2 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 RAD51 RAE1 RAN RANBP2 RBM15B RBM8A SGTA SH2D3A SRPK2 SRSF1 SRSF3 SRSF7 STRAP THOC5 TIFA TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN4 UPF3A XIST ZBED2	4 interacting genes: CALB1 IMPA2 NXF1 S100B
Entrez ID		10482	3612
HPRD ID		04035	03641
Ensembl ID		ENSG00000162231	ENSG00000133731
Uniprot IDs		Q59E96 Q9UBU9	A0A024R830 A0A140VJL8 P29218
PDB IDs		1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7 4WYK 6E5U	1AWB 1IMA 1IMB 1IMC 1IMD 1IME 1IMF 2HHM 4AS4 6GIU 6GJ0
Enriched GO Terms of Interacting Partners?
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