IMPA1 and IMPA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, biochemical)

		IMPA1	IMPA2
Description		inositol monophosphatase 1	inositol monophosphatase 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Cytosol
	Molecular Function	Magnesium Ion Binding Protein Binding Inositol Monophosphate 1-phosphatase Activity Manganese Ion Binding Lithium Ion Binding Identical Protein Binding Protein Homodimerization Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity	Protein Binding Inositol Monophosphate 1-phosphatase Activity Protein Homodimerization Activity Metal Ion Binding Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity
	Biological Process	Inositol Metabolic Process Inositol Biosynthetic Process Phosphatidylinositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation	Inositol Metabolic Process Inositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation
Pathways		Synthesis of IP2, IP, and Ins in the cytosol	Synthesis of IP2, IP, and Ins in the cytosol
Drugs		Lithium L-Myo-Inositol-1-Phosphate	Lithium
Diseases
GWAS		Ovarian cancer ( 23535730)	Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744) Stroke ( 17434096)
Interacting Genes		4 interacting genes: CALB1 IMPA2 NXF1 S100B	4 interacting genes: HERPUD1 IMPA1 TNFRSF14 UBA3
Entrez ID		3612	3613
HPRD ID		03641	09329
Ensembl ID		ENSG00000133731	ENSG00000141401
Uniprot IDs		A0A024R830 A0A140VJL8 P29218	O14732
PDB IDs		1AWB 1IMA 1IMB 1IMC 1IMD 1IME 1IMF 2HHM 4AS4 6GIU 6GJ0	2CZH 2CZI 2CZK 2DDK 2FVZ
Enriched GO Terms of Interacting Partners?
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