TUBGCP3 and CDC16

		TUBGCP3	CDC16
Description		tubulin gamma complex associated protein 3	cell division cycle 16
Image		No pdb structure
GO Annotations	Cellular Component	Equatorial Microtubule Organizing Center Gamma-tubulin Complex Cytoplasm Centrosome Centriole Spindle Polar Microtubule Cytosol Gamma-tubulin Small Complex Membrane	Nucleoplasm Anaphase-promoting Complex Cytoplasm Centrosome Cytosol Spindle Microtubule
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitotic Cell Cycle Microtubule Nucleation Single Fertilization Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Microtubule Nucleation By Interphase Microtubule Organizing Center	Ubiquitin-dependent Protein Catabolic Process Metaphase/anaphase Transition Of Mitotic Cell Cycle Protein Ubiquitination Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Mitotic Metaphase/anaphase Transition Cell Division Protein K11-linked Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Inactivation of APC/C via direct inhibition of the APC/C complex APC/C:Cdc20 mediated degradation of Cyclin B Autodegradation of Cdh1 by Cdh1:APC/C APC/C:Cdc20 mediated degradation of Securin APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Cdc20:Phospho-APC/C mediated degradation of Cyclin A Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Regulation of APC/C activators between G1/S and early anaphase APC/C:Cdc20 mediated degradation of mitotic proteins Phosphorylation of the APC/C APC-Cdc20 mediated degradation of Nek2A Separation of Sister Chromatids Senescence-Associated Secretory Phenotype (SASP) CDK-mediated phosphorylation and removal of Cdc6 Transcriptional Regulation by VENTX Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 20858683)	Metabolite levels ( 23823483) Prudent dietary pattern ( 28644415) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		10 interacting genes: AKAP9 ARTN CDC16 IMMT LRBA PCNT PROZ RASA3 TUBG1 TUBG2	23 interacting genes: ANAPC10 ANAPC11 ANAPC7 BUB1B C11orf49 CDC20 CDC23 CDC27 DAB2 DNAJA1 FBXO5 FTH1 HINT1 LINC00839 MAD2L1 MTNR1B PPP5C SKIL SMAD2 SMAD3 TUBGCP3 UBE2S XRCC5
Entrez ID		10426	8881
HPRD ID		10289	04587
Ensembl ID		ENSG00000126216	ENSG00000130177
Uniprot IDs		A0A087WU06 B4DYP7 Q96CW5	A0A024RDZ2 A0A3B3ISD2 B2RCW0 Q13042
PDB IDs			3HYM 4UI9 5A31 5G04 5G05 5KHR 5KHU 5L9T 5L9U 5LCW 6Q6G 6Q6H
Enriched GO Terms of Interacting Partners?
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