UBAC1 and CPSF6

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		UBAC1	CPSF6
Description		UBA domain containing 1	cleavage and polyadenylation specific factor 6
Image
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome	Nucleus Nucleoplasm Perichromatin Fibrils Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane Nuclear Speck Interchromatin Granule Paraspeckles Ribonucleoprotein Complex
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding Ribosomal Large Subunit Binding Exon-exon Junction Complex Binding
	Biological Process	Protein Ubiquitination	MRNA Processing Positive Regulation Of RNA Export From Nucleus Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Height ( 18391951) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Pneumoconiosis in silica exposure ( 24986923) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		19 interacting genes: AIRE APP CDKN1B CPSF6 CSNK2A1 DAZAP2 DVL2 HTT LAPTM5 MAP3K1 NEDD4L PMPCA RNF11 RNF123 SMURF1 TRIM2 TRIM39 UBC ZDHHC17	23 interacting genes: APBB1 ARMC7 CSNK2A1 EWSR1 GIN1 ITCH ITSN2 KLHL12 NCK2 NEDD4 NUDT21 OTUB2 PLSCR1 PPIL1 PRPF40A SRSF7 TCERG1 TOLLIP UBAC1 UBQLN4 WBP4 WWP1 WWP2
Entrez ID		10422	11052
HPRD ID		12170	05401
Ensembl ID		ENSG00000130560	ENSG00000111605
Uniprot IDs		A0A140VK64 Q9BSL1	Q16630
PDB IDs		2DAI	3P5T 3P6Y 3Q2S 3Q2T 4B4N 4U0A 4U0B 4WYM 6AY9 6GX9
Enriched GO Terms of Interacting Partners?
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