NDRG1 and NCL

Number of citations of the paper that reports this interaction (PubMedID 17220478)
24

Data Source:
HPRD (in vivo)

		NDRG1	NCL
Description		N-myc downstream regulated 1	nucleolin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Microtubule Plasma Membrane Adherens Junction Microtubule Cytoskeleton Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Glutamatergic Synapse	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cell Cortex Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding Microtubule Binding Rab GTPase Binding Gamma-tubulin Binding Cadherin Binding	RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding DNA Topoisomerase Binding MRNA 5'-UTR Binding
	Biological Process	Signal Transduction Negative Regulation Of Cell Proliferation Response To Metal Ion DNA Damage Response, Signal Transduction By P53 Class Mediator Peripheral Nervous System Myelin Maintenance Regulation Of Apoptotic Process Mast Cell Activation Cellular Response To Hypoxia Postsynapse Organization	Angiogenesis Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Cellular Response To Leukemia Inhibitory Factor
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Estimated glomerular filtration rate ( 31015462) Nontyphoidal Salmonella bacteraemia ( 29523850) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)	Attention deficit hyperactivity disorder ( 23728934) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Eating disorders (purging via substances) ( 23568457) Height ( 31562340) Noise-induced hearing loss ( 26121033)
Interacting Genes		71 interacting genes: ACSL3 ACTG1 AP1M2 AP2M1 APOA1 APOA2 ARL4D ATP1A1 CANX CDH1 CLTC CNDP2 COPB2 CTNNB1 DDX1 DDX5 DLST EEF1G EEF2 EIF2S3 EIF3E EWSR1 FASN GPAA1 GSK3B HNRNPF HNRNPH1 HNRNPU HSD17B4 HSP90AA1 HSPA5 ILF3 KIF5B LDHA MAOA MLH1 MME MYC NCL NR4A1 PABPC1 PHYHIP PKM PPP2R2A PRKACA PSMC2 PSMC3 PSMD2 RPL24 RPL3 RPL4 RPN2 RPS16 RPS20 RPS26 RPS3 RPS6 RPS8 RTN1 RUVBL2 S100B SEC23A SGK1 SHMT2 TAF9 TARS1 TLE3 UPF1 VCP XRCC5 ZNF155	53 interacting genes: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CLK1 CSNK2A1 CSNK2A2 ERG ESR1 ETS1 FMR1 GRB2 GZF1 GZMA H1-2 H2AC20 H2AX H2BC21 H3-4 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PRMT5 PTGS1 RAD51 S100A11 SREK1 SRPK2 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689
Entrez ID		10397	4691
HPRD ID		05586	01245
Ensembl ID		ENSG00000104419	ENSG00000115053
Uniprot IDs		B3KWB2 Q8N959 Q92597	B3KM80 P19338
PDB IDs			2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?
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