TUBA1B and SUMO2

Number of citations of the paper that reports this interaction (PubMedID 19394292)
74

Data Source:
BioGRID (pull down)

		TUBA1B	SUMO2
Description		tubulin alpha 1b	small ubiquitin like modifier 2
Image
GO Annotations	Cellular Component	Cytoplasm Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Raft	Nucleus Nucleoplasm PML Body
	Molecular Function	Double-stranded RNA Binding GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Ubiquitin Protein Ligase Binding	Transcription Corepressor Binding RNA Binding Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cell Division Cellular Response To Interleukin-4	Protein Sumoylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins	Vitamin D (calciferol) metabolism SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of SUMOylation proteins SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER
Drugs		Epothilone D Patupilone CYT997 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS		Bipolar disorder ( 31043756)	Gamma glutamyl transferase levels ( 29403010)
Interacting Genes		31 interacting genes: A2M AGTRAP CCT2 EPN2 ESR1 FYN GRM7 GZMM HDAC6 MAPT MINK1 MTCL1 MYC NFKBIA PFDN5 PIK3R1 PSEN1 PTEN PTP4A1 PTPRF PXN SIAH1 SLX1B SMAD2 SNAP91 SRPK2 SUMO2 TERT TMEM253 TOM1L1 TUBG1	179 interacting genes: ABRAXAS1 AHNAK ALAS1 ANAPC2 ANXA1 ATF7IP ATRX ATXN7 BABAM2 BAD BAZ1A BAZ1B BLM BRCC3 C18orf25 CAD CARS1 CCNE2 CENPC CHAF1A CHAF1B CHAMP1 CHD3 CHD4 CMTM6 CSNK2B CTNND1 CUL3 CUX1 DAXX DCD DDX17 DDX21 DDX3X DNM1L EEF1A1 EEF1G EGLN3 EME1 ENO1 EP300 ERCC4 EXOSC10 EXOSC9 FOS GATAD2B HDAC1 HDAC2 HDAC4 HDAC9 HIPK2 HNRNPF HNRNPH1 HNRNPK HOMEZ HP1BP3 HSF2 HSP90AB1 HSPA1A HSPA8 HSPA9 IPO5 JUN KALRN KDM1A KIF18B LAS1L LEF1 MAF1 MAST2 MDC1 MDN1 MKI67 MRE11 MSH2 MSX1 MTA1 MTA2 MUS81 MYB NBN NFE2L2 NOL9 NOP2 NUMA1 PARN PELP1 PFKM PHF5A PHF8 PIAS1 PIAS2 PIAS3 PIAS4 PML POGZ PRKDC RAD50 RAD51 RAD54L2 RANBP2 RANGAP1 RBBP4 RBBP7 RCOR1 RCOR2 RCOR3 RNF111 RNF168 RNF216 RNF4 RNF8 RPL3 RPL4 RUVBL1 SAE1 SENP1 SENP2 SENP3 SENP5 SENP6 SENP7 SETDB1 SETX SIMC1 SLC22A2 SLX4IP SMCHD1 SOBP SOX10 SOX6 SP100 SSRP1 SUPT16H TDG TDP2 TEAD3 TEX10 TMPO TNIP1 TOP2A TOP2B TOPORS TP53BP1 TP53BP2 TPR TRAF1 TRIM26 TRIM28 TRIM63 TRIML2 TUBA1B TUBB TUBB4B TUBB6 UBA2 UBE2I USP11 USP25 USP28 USP7 USPL1 VIM WRN XRCC5 XRCC6 ZBED1 ZBTB2 ZBTB25 ZBTB33 ZCCHC12 ZCCHC7 ZHX1 ZMAT3 ZMYM3 ZMYM4 ZMYM5 ZNF451 ZNF496
Entrez ID		10376	6613
HPRD ID		03960	04332
Ensembl ID		ENSG00000123416	ENSG00000188612
Uniprot IDs		P68363	A0A024R8S3 P61956
PDB IDs		2E4H 5IJ0 5IJ9 5N5N 6E7B 6E7C 6I2I 6J4V 6QUS 6QUY 6QVE 6QVJ 6S8L	1WM2 1WM3 1WZ0 1Z5Q 2AWT 2CKH 2D07 2IO0 2IO3 2IYD 2N1W 2N9E 2RPQ 3UIN 3UIO 3ZO5 4BKG 4NPN 5D2M 5ELU 5EQL 5GHB 5GHC
Enriched GO Terms of Interacting Partners?
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