CLEC4M and CD209

Number of citations of the paper that reports this interaction (PubMedID 11384997)
137

Data Source:
HPRD (in vitro)

		CLEC4M	CD209
Description		C-type lectin domain family 4 member M	CD209 molecule
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Integral Component Of Plasma Membrane Membrane Host Cell	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Host Cell
	Molecular Function	Virus Receptor Activity Mannose Binding Carbohydrate Binding ICAM-3 Receptor Activity Signaling Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding Calcium-dependent Protein Binding	Virus Receptor Activity Protein Binding Mannose Binding Carbohydrate Binding Peptide Antigen Binding Virion Binding Metal Ion Binding
	Biological Process	Adaptive Immune Response Endocytosis Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Morphology Or Physiology Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus	Stimulatory C-type Lectin Receptor Signaling Pathway Adaptive Immune Response Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Modulation By Virus Of Host Morphology Or Physiology Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Viral Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion
Pathways			CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Monocyte count ( 27863252) vWF levels ( 30586737)	Blood protein levels ( 30072576 29875488)
Interacting Genes		3 interacting genes: CD209 ICAM3 ITGAM	7 interacting genes: CEACAM1 CLEC4M CLU ICAM2 ICAM3 ITGAM VAC14
Entrez ID		10332	30835
HPRD ID		12060	05241
Ensembl ID		ENSG00000104938	ENSG00000090659
Uniprot IDs		B4E2Z5 H7BXU4 Q9H2X3	B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12
PDB IDs		1K9J 1SL6 1XAR 1XPH 1Z0Y 3JQH	1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV
Enriched GO Terms of Interacting Partners?
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