TNIP1 and SNIP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TNIP1	SNIP1
Description		TNFAIP3 interacting protein 1	Smad nuclear interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytosol U2-type Precatalytic Spliceosome
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Mitogen-activated Protein Kinase Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	MyD88-dependent Toll-like Receptor Signaling Pathway Translation Defense Response Inflammatory Response Leukocyte Cell-cell Adhesion Glycoprotein Biosynthetic Process Protein Deubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Inflammatory Response Negative Regulation Of ERK1 And ERK2 Cascade Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Protein Deubiquitination	MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II I-kappaB Kinase/NF-kappaB Signaling Production Of MiRNAs Involved In Gene Silencing By MiRNA
Pathways		Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 29566793) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Cutaneous psoriasis ( 26626624) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Inflammatory skin disease ( 25574825) Myasthenia gravis ( 23055271) Neutrophil percentage of granulocytes ( 27863252) Psoriasis ( 25854761 25903422 25574825 23143594 19169254) Psoriasis vulgaris ( 26626624 29031612) Psoriatic arthritis ( 26626624) Rheumatoid arthritis (ACPA-positive) ( 23143596) SjÃ¶gren's syndrome ( 24097067) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 26606652 23273568 26502338 28714469 19838193 19838195) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 21750679 31672989 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655)	Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		66 interacting genes: ABHD17A ADH6 AP1M1 BYSL CCDC112 CCDC121 CCNG1 CDIP1 CDKN1A CFAP53 EFEMP1 EHHADH FAM161A FAM168A FUS GABARAPL1 GABARAPL2 GIT2 GTF2B GTF2H1 HDAC1 HDDC3 IKBKG KIFC3 MAGEB18 MAGEH1 MAP1LC3A MAP1LC3B MAP3K1 MAPK1 MAPK10 MCM10 MOB1B MOB3C MORF4L1 MORF4L2 NDC80 NFKB1 NIFK NME7 NOD2 PIN1 PNKP RABAC1 RALBP1 RARA RARG RBFOX1 RNF11 RPL5 S100B SELPLG SNIP1 SUMO2 SYT6 TCEA2 TCEANC2 TNFAIP3 TNIP3 TTF2 TXLNA TYRO3 UBC VPS33B ZBTB25 ZNHIT1	48 interacting genes: AKIRIN1 CDK6 CHERP CREBBP DVL2 EIF3C EP300 EVA1B FAF1 GMEB1 HIPK1 HIPK3 JUN MAX MFAP1 MYC NFATC2 OXSM PIAS1 PIAS2 PIAS3 PIAS4 POU3F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SH3D21 SMAD1 SMAD2 SMAD4 SON SP100 SRPK2 SRRM2 STK40 TDG TNIP1 TOPORS TTC14 UBE2I ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451 ZNF496
Entrez ID		10318	79753
HPRD ID		09216	06999
Ensembl ID		ENSG00000145901	ENSG00000163877
Uniprot IDs		A0A0A0MRZ4 A8K4N4 B7Z8K2 Q15025	B1AK66 Q8TAD8
PDB IDs			5Z56 5Z57 5Z58 6FF7
Enriched GO Terms of Interacting Partners?
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