SNAPC5 and BRCC3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		SNAPC5	BRCC3
Description		small nuclear RNA activating complex polypeptide 5	BRCA1/BRCA2-containing complex subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body	Ubiquitin Ligase Complex Nuclear Ubiquitin Ligase Complex Spindle Pole Nucleus Nucleoplasm Cytoplasm Cytosol BRCA1-A Complex BRISC Complex
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity DNA-binding Transcription Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Enzyme Regulator Activity Polyubiquitin Modification-dependent Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Metal Ion Binding Lys63-specific Deubiquitinase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III	DNA Repair Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Cell Cycle Response To X-ray Response To Ionizing Radiation Protein Deubiquitination Positive Regulation Of DNA Repair Regulation Of Catalytic Activity Cell Division Protein K63-linked Deubiquitination Histone H2A K63-linked Deubiquitination Signal Transduction Involved In G2 DNA Damage Checkpoint
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs			Zinc
Diseases
GWAS			Venous thromboembolism ( 31676865)
Interacting Genes		14 interacting genes: AMOT BATF BRCC3 CYTH4 DDIT3 JUN NDEL1 NMI NOL4 NUDT10 NUP62 SNAPC1 SNAPC4 ZNRD2	9 interacting genes: BRCA1 FANCG IFNAR1 NUMA1 SNAPC5 SUMO2 UBC UBE2D1 UIMC1
Entrez ID		10302	79184
HPRD ID		16183	06465
Ensembl ID		ENSG00000174446	ENSG00000185515
Uniprot IDs		A0A024R5X1 O75971	P46736
PDB IDs			6H3C 6R8F
Enriched GO Terms of Interacting Partners?
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