RABEPK and PIKFYVE

Number of citations of the paper that reports this interaction (PubMedID 14530284)
27

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		RABEPK	PIKFYVE
Description		Rab9 effector protein with kelch motifs	phosphoinositide kinase, FYVE-type zinc finger containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Endosome Membrane Transport Vesicle Trans-Golgi Network Membrane	Golgi Membrane Cytosol Cell-cell Junction Endosome Membrane Vesicle Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function		1-phosphatidylinositol-3-phosphate 5-kinase Activity Protein Binding ATP Binding Zinc Ion Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity
	Biological Process	Receptor-mediated Endocytosis Vesicle Docking Involved In Exocytosis	Phosphatidylinositol Biosynthetic Process Receptor-mediated Endocytosis Myelin Assembly Protein Localization To Nucleus Intracellular Signal Transduction Phosphatidylinositol-3-phosphate Biosynthetic Process Retrograde Transport, Endosome To Golgi Phosphatidylinositol Phosphorylation Phosphatidylinositol 5-phosphate Metabolic Process Regulation Of Autophagosome Assembly
Pathways		Retrograde transport at the Trans-Golgi-Network	Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases			Fleck corneal dystrophy (FCD); Francois-Neetens speckled corneal dystrophy
GWAS			Adult asthma ( 27611488) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		7 interacting genes: GLUL PIKFYVE POR PRKRA RAB9A TMEM98 ZYX	4 interacting genes: APP CDK5 RABEPK VAC14
Entrez ID		10244	200576
HPRD ID		09337	17852
Ensembl ID		ENSG00000136933	ENSG00000115020
Uniprot IDs		A0A024R8A0 A0A0S2Z4Z1 A0A0S2Z4Z5 Q7Z6M1	Q9Y2I7
PDB IDs
Enriched GO Terms of Interacting Partners?
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