PIKFYVE

Description		phosphoinositide kinase, FYVE-type zinc finger containing
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Cell-cell Junction Endosome Membrane Vesicle Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	1-phosphatidylinositol-3-phosphate 5-kinase Activity Protein Binding ATP Binding Zinc Ion Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Phosphatidylinositol-3,5-bisphosphate 5-phosphatase Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Receptor-mediated Endocytosis Myelin Assembly Protein Localization To Nucleus Intracellular Signal Transduction Phosphatidylinositol-3-phosphate Biosynthetic Process Retrograde Transport, Endosome To Golgi Phosphatidylinositol Phosphorylation Phosphatidylinositol 5-phosphate Metabolic Process Regulation Of Autophagosome Assembly
Pathways		Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases		Fleck corneal dystrophy (FCD); Francois-Neetens speckled corneal dystrophy
GWAS		Adult asthma ( 27611488) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		4 interacting genes: APP CDK5 RABEPK VAC14
Entrez ID		200576
HPRD ID		17852
Ensembl ID		ENSG00000115020
Uniprot IDs		Q9Y2I7
PDB IDs
Enriched GO Terms of Interacting Partners?
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