GPHN and ENAH

Number of citations of the paper that reports this interaction (PubMedID 12967995)
43

Data Source:
HPRD (in vitro, in vivo)

		GPHN	ENAH
Description		gephyrin	ENAH actin regulator
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Cell Junction Dendrite Postsynaptic Membrane Postsynaptic Specialization Postsynaptic Specialization Membrane	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium Cell Junction Filopodium Synapse
	Molecular Function	Protein Binding ATP Binding Nitrate Reductase Activity Molybdopterin Cofactor Binding Metal Ion Binding Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding WW Domain Binding
	Biological Process	Mo-molybdopterin Cofactor Biosynthetic Process Establishment Of Synaptic Specificity At Neuromuscular Junction Response To Metal Ion Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Molybdopterin Cofactor Biosynthetic Process Oxidation-reduction Process Glycine Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Postsynaptic Neurotransmitter Receptor Diffusion Trapping	Axon Guidance Actin Polymerization Or Depolymerization Actin Polymerization-dependent Cell Motility
Pathways		Molybdenum cofactor biosynthesis	Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors
Drugs		Formic Acid Imidazole Propanoic Acid
Diseases		Hyperekplexia
GWAS		Depression (quantitative trait) ( 23290196) Pneumococcal meningitis ( 31092817) Tandem gait ( 26219847) Waist circumference adjusted for body mass index ( 28552196)	Delirium ( 29631748) Depression in smokers ( 30219690) Neuroticism ( 27067015) Obesity-related traits ( 23251661)
Interacting Genes		13 interacting genes: ACADVL ARHGEF9 DYNLL1 DYNLL2 ENAH GABARAP GLRB KHDRBS1 MTOR PFN1 PIN1 SPATS1 TUBA4A	26 interacting genes: ABI1 ABI2 ABI3 ABL1 APBB1 BAIAP2 DNMBP EVL FAT1 FYB1 GPHN HMGB1 MAPK1 PFN1 PRPF40A RAC1 RAD51 ROBO4 SPTA1 TERF2IP TES VASP WAS XIRP1 YAP1 ZYX
Entrez ID		10243	55740
HPRD ID		04893	12360
Ensembl ID		ENSG00000171723	ENSG00000154380
Uniprot IDs		Q9NQX3	A0A4D6J698 Q8N8S7
PDB IDs		1JLJ	2HO2 2IYB 2XQN 4MY6 5N91 5N9C 5N9P 5NAJ 5NBF 5NBX 5NC2 5NC7 5NCF 5NCG 5NCP 5ND0 5NDU 5NEG
Enriched GO Terms of Interacting Partners?
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