ZNF263 and CLK2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF263	CLK2
Description		zinc finger protein 263	CDC like kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nuclear Body Nuclear Speck
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated	Protein Phosphorylation Response To Ionizing Radiation Peptidyl-tyrosine Phosphorylation Response To Retinoic Acid Regulation Of RNA Splicing Negative Regulation Of Gluconeogenesis Protein Autophosphorylation
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		15 interacting genes: CLK2 CLK3 DVL2 EFEMP2 GPATCH2L NME7 PCBD1 PLEKHF2 SCAND1 SPG21 SUFU TCAF1 TRIM41 ZNF446 ZSCAN1	28 interacting genes: AKT1 CLK3 CPSF7 ECE1 GMCL1 KLHL2 LNX1 LUZP4 MRPL4 PRPF38A PTPN1 RBM39 RNPS1 RSRP1 SDCBP SRPK2 SRRM1 TRIM27 U2AF1 UBE2I UBL5 YTHDC1 YWHAG ZNF263 ZNF394 ZNF398 ZNF473 ZRSR2
Entrez ID		10127	1196
HPRD ID		05008	04289
Ensembl ID		ENSG00000006194	ENSG00000176444
Uniprot IDs		D3DUC1 O14978	A8K7I0 B7Z8N6 P49760
PDB IDs			3NR9 5UNP 6FYI 6FYK 6FYL 6KHE
Enriched GO Terms of Interacting Partners?
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